The COVID-19 pandemic has elucidated a number of challenges and the need for adaptive health systems worldwide, particularly when there is a “shock,” such as an outbreak or pandemic, to the health system. This talk will cover examples of AI used to address Global Health and focus on recently published work on COVID-19 in Nature - Scientific data (https://www.nature.com/articles/s41597-021-00878-y), on our  Worldwide Non-pharmaceutical Interventions Tracker for COVID-19 (WNTRAC), https://ibm.github.io/wntrac.