Marianna is leading the AI for single-cell research team at IBM Research Europe in Zurich. The overarching goal of her team is modeling spatiotemporal tumor heterogeneity across different scales of biological organization, and understanding how it affects cancer initiation, progression, and response to treatment. To achieve that, her team combines machine learning and deep learning approaches to develop computational methods able to extract biologically meaningful patterns from large-scale, heterogeneous, and noisy single-cell data, with or without spatial resolution.